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Investment theme · updated October 18, 2026
Obesity drug stocks (GLP-1): prices and rankings
The theme covers companies that make or develop GLP-1 drugs, used for diabetes and weight loss, plus those that sell or distribute them. Demand has grown very fast, and competition is now moving toward pills and less frequent doses.
We track 6 companies in obesity treatments. In the last session, on Friday, October 16, 2 of 6 closed higher, and the theme moved -0.56% on a market-cap-weighted basis. The median 1-year return is +16%.
Companies6
Last session-0.56%
1-year return+16%
Median P/E21.4
Median dividend3.00%
Total market cap1.78 T $
The biggest gainers and losers in obesity treatments in the last session
The biggest gains and losses in the latest session, among companies worth more than $2 billion.
Top gainers, Friday, October 16
Zealand Pharma A/SZEAL · CO306.00 DKK+3.45%2
AstraZeneca PLCAZN · LSE£135.80+0.85%The largest companies in obesity treatments
The top 10 companies on each measure.
| # | Company | Price | Friday | 1 year | Market cap | P/E | Dividend |
|---|---|---|---|---|---|---|---|
| 1 |  Eli Lilly and CompanyLLY · Healthcare | $1,136 | -0.73% | +42% | 1.01 T $ | 40.1 | 0.65% |
| 2 | AstraZeneca PLCAZN · Healthcare | £135.80 | +0.85% | +27% | 283.1 B $ | 27.5 | 1.70% |
| 3 |  Amgen IncAMGN · Healthcare | $337.70 | -1.99% | +19% | 182.3 B $ | 23.4 | 3.00% |
| 4 | Novo Nordisk A/SNOVO-B · Healthcare | 285.60 DKK | -0.57% | -42% | 148.8 B $ | 7.9 | 5.90% |
| 5 |  Pfizer IncPFE · Healthcare | $25.60 | -0.39% | +13% | 145.9 B $ | 19.5 | 6.65% |
| 6 | Zealand Pharma A/SZEAL · Healthcare | 306.00 DKK | +3.45% | -32% | 3.3 B $ | 3.4 | - |
| 1 | Pfizer IncPFE · Healthcare | $25.60 | -0.39% | +13% | 145.9 B $ | 19.5 | 6.65% |
| 2 | Novo Nordisk A/SNOVO-B · Healthcare | 285.60 DKK | -0.57% | -42% | 148.8 B $ | 7.9 | 5.90% |
| 3 | Amgen IncAMGN · Healthcare | $337.70 | -1.99% | +19% | 182.3 B $ | 23.4 | 3.00% |
| 4 | AstraZeneca PLCAZN · Healthcare | £135.80 | +0.85% | +27% | 283.1 B $ | 27.5 | 1.70% |
| 5 | Eli Lilly and CompanyLLY · Healthcare | $1,136 | -0.73% | +42% | 1.01 T $ | 40.1 | 0.65% |
| 1 | Eli Lilly and CompanyLLY · Healthcare | $1,136 | -0.73% | +42% | 1.01 T $ | 40.1 | 0.65% |
| 2 | AstraZeneca PLCAZN · Healthcare | £135.80 | +0.85% | +27% | 283.1 B $ | 27.5 | 1.70% |
| 3 | Amgen IncAMGN · Healthcare | $337.70 | -1.99% | +19% | 182.3 B $ | 23.4 | 3.00% |
| 4 | Pfizer IncPFE · Healthcare | $25.60 | -0.39% | +13% | 145.9 B $ | 19.5 | 6.65% |
| 5 | Zealand Pharma A/SZEAL · Healthcare | 306.00 DKK | +3.45% | -32% | 3.3 B $ | 3.4 | - |
| 6 | Novo Nordisk A/SNOVO-B · Healthcare | 285.60 DKK | -0.57% | -42% | 148.8 B $ | 7.9 | 5.90% |
| 1 | Zealand Pharma A/SZEAL · Healthcare | 306.00 DKK | +3.45% | -32% | 3.3 B $ | 3.4 | - |
| 2 | Novo Nordisk A/SNOVO-B · Healthcare | 285.60 DKK | -0.57% | -42% | 148.8 B $ | 7.9 | 5.90% |
| 3 | Pfizer IncPFE · Healthcare | $25.60 | -0.39% | +13% | 145.9 B $ | 19.5 | 6.65% |
| 4 | Amgen IncAMGN · Healthcare | $337.70 | -1.99% | +19% | 182.3 B $ | 23.4 | 3.00% |
| 5 | AstraZeneca PLCAZN · Healthcare | £135.80 | +0.85% | +27% | 283.1 B $ | 27.5 | 1.70% |
| 6 | Eli Lilly and CompanyLLY · Healthcare | $1,136 | -0.73% | +42% | 1.01 T $ | 40.1 | 0.65% |
All stocks in obesity treatments
Sorted by market cap. Each one has its own page with the full analysis.
How we pick the companies in a theme
Each list is put together by hand, from companies that earn a large share of their revenue from the theme or lead it. We review it as the market changes. Only companies we analyze appear on the page.
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Where to buy stocks: recommended brokers
Regulated brokers, with their stock trading fees, minimum deposit and the authority that supervises them.
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Frequently asked questions about stocks in obesity treatments
What are the largest companies in obesity treatments?
By market capitalization, the largest are Eli Lilly and Company, AstraZeneca PLC and Amgen Inc.
How have stocks in obesity treatments performed over the past year?
The median 1-year return is +16%. In the last session, on Friday, October 16, 2 of 6 companies closed higher, and the theme moved -0.56% on a market-cap-weighted basis.
What dividends do companies in obesity treatments pay?
5 of the 6 companies pay a dividend, with a median yield of 3.00%. The highest yield belongs to Pfizer Inc, at 6.65% a year.
How do you invest in stocks in obesity treatments?
Through an account with a regulated broker: buy the companies you choose or a thematic ETF that holds many of them. Popular themes can swing hard, so it pays not to put all your money in one place.
The data on this page is for information only and is not investment advice. Prices may be delayed.